6u3n

X-ray diffraction
2.8Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-208064 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
T-CELL RECEPTOR, LS2.8/3.15 alpha Chain: D
Molecule details ›
Chain: D
Length: 206 amino acids
Theoretical weight: 22.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
T-CELL RECEPTOR, LS2.8/3.15 beta Chain: E
Molecule details ›
Chain: E
Length: 244 amino acids
Theoretical weight: 27.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
HLA class II histocompatibility antigen, DQ alpha 1 chain Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 21.5 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P01909 (Residues: 24-206; Coverage: 79%)
Gene name: HLA-DQA1
Sequence domains:
Ig-like domain-containing protein Chain: B
Molecule details ›
Chain: B
Length: 206 amino acids
Theoretical weight: 23.7 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: O19712 (Residues: 1-192; Coverage: 84%)
Gene name: HLA-DQB1
Sequence domains:
Peptide Chain: C
Molecule details ›
Chain: C
Length: 20 amino acids
Theoretical weight: 2.04 KDa
Source organism: Pseudomonas fluorescens
Expression system: Trichoplusia ni

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: C2221
Unit cell:
a: 59.98Å b: 239.47Å c: 147.46Å
α: 90° β: 90° γ: 90°
Expression systems:
  • Escherichia coli
  • Trichoplusia ni