› 6uhh

X-ray diffraction
3.14Å resolution

Crystal Structure of Human RYR Receptor 3 ( 848-1055) in Complex with ATP

Released:
DOI: 10.2210/pdb6uhh/pdb
PDB entry 6uhh coloured by chain, front view.
PDB entry 6uhh coloured by chain, side view.
PDB entry 6uhh coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wu R, Kim Y, Jedrzejczak R, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172280 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ryanodine receptor 3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 211 amino acids
Theoretical weight: 24.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15413 (Residues: 848-1055; Coverage: 4%)
Gene names: HBRR, RYR3
Sequence domains: RyR domain

Ligands and Environments

4 bound ligands:
Ligand ATP 2 x ATP
Ligand GOL 13 x GOL
Ligand TRS 1 x TRS
Ligand PEG 1 x PEG
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 62.043Å b: 61.855Å c: 279.128Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.233 0.287
Expression system: Escherichia coli BL21(DE3)

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