Function and Biology Details
Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Receptor-type tyrosine-protein phosphatase alpha (preferred)
PDBe Complex ID:
PDB-CPX-148370 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Receptor-type tyrosine-protein phosphatase alpha
Molecule details ›
Chains: A, B
Length: 601 amino acids
Theoretical weight: 69.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Protein-tyrosine phosphatase
Length: 601 amino acids
Theoretical weight: 69.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P18433 (Residues: 211-802; Coverage: 76%)
Sequence domains: Protein-tyrosine phosphatase
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 5.0.1
Expression system: Escherichia coli BL21
