6vu5

Electron Microscopy
3.5Å resolution

Structure of G-alpha-q bound to its chaperone Ric-8A

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-156135 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Synembryn-A Chain: A
Molecule details ›
Chain: A
Length: 482 amino acids
Theoretical weight: 53.91 KDa
Source organism: Rattus norvegicus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q80ZG1 (Residues: 1-438, 439-450; Coverage: 85%)
Gene name: Ric8a
Sequence domains: Guanine nucleotide exchange factor synembryn
Guanine nucleotide-binding protein G(q) subunit alpha Chain: B
Molecule details ›
Chain: B
Length: 359 amino acids
Theoretical weight: 42.2 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P50148 (Residues: 1-359; Coverage: 100%)
Gene names: GAQ, GNAQ
Sequence domains: G-protein alpha subunit

Ligands and Environments

No bound ligands
2 modified residues:

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-21387
Expression system: Trichoplusia ni