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6whu

Electron Microscopy
3.93Å resolution

GluN1b-GluN2B NMDA receptor in complex with SDZ 220-040 and L689,560, class 1

Released:
Source organism: Rattus norvegicus
Related structures: EMD-21676

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-152911 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Glutamate receptor ionotropic, NMDA 1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 959 amino acids
Theoretical weight: 108.09 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P35439 (Residues: 1-190, 191-938; Coverage: 100%)
  • Best match: P35439-2 (Residues: 1-959)
Gene names: Grin1, Nmdar1
Sequence domains:
Glutamate receptor ionotropic, NMDA 2B Chains: B, D
Molecule details ›
Chains: B, D
Length: 883 amino acids
Theoretical weight: 98.85 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q00960 (Residues: 27-852; Coverage: 57%)
Gene name: Grin2b
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
3 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.93Å
Relevant EMDB volumes: EMD-21676
Expression system: Spodoptera frugiperda