› 6wvg

X-ray diffraction
2.9Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148566 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Green fluorescent protein; Leukocyte surface antigen CD53 Chains: A, B
Molecule details ›
Chains: A, B
Length: 457 amino acids
Theoretical weight: 51.47 KDa
Source organisms: Expression system: Komagataella pastoris
UniProt:
  • Canonical: P42212 (Residues: 1-144, 145-230; Coverage: 97%)
  • Canonical: P19397 (Residues: 1-219; Coverage: 100%)
Gene names: CD53, GFP, MOX44, TSPAN25
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand OLC 5 x OLC
Ligand NAG 2 x NAG
1 modified residue:
Ligand CRO 2 x CRO

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 49.31Å b: 209.77Å c: 73.28Å
α: 90° β: 100.29° γ: 90°
R-values:
R R work R free
0.218 0.216 0.269
Expression system: Komagataella pastoris

Quick links

Citations

3 review citations

Stabilization and structure determination of integral membrane proteins by termini restraining.
Liu et al. (2022)
2 more

5 mentions without citation

Regulation of ADAM10 by the TspanC8 Family of Tetraspanins and Their Therapeutic Potential.
Harrison et al. (2021)
4 more