› 6y07

Solution NMR

Designing a Granulopoietic Protein by Topological Rescaffolding 1: Sohair

Released:
DOI: 10.2210/pdb6y07/pdb
PDB entry 6y07 coloured by chain, ensemble of 19 models, front view.
PDB entry 6y07 coloured by chain, ensemble of 19 models, side view.
PDB entry 6y07 coloured by chain, ensemble of 19 models, top view.
Source organism: synthetic construct
Primary publication:
Design of novel granulopoietic proteins by topological rescaffolding.
Hernandez Alvarez B, Skokowa J, Coles M, Mir P, Nasri M, Maksymenko K, Weidmann L, Rogers KW, Welte K, Lupas AN, Müller P, ElGamacy M
OpenAccess logo PLoS Biol 18 e3000919 (2020)
PMID: 33351791

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167820 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
sohair Chain: A
Molecule details ›
Chain: A
Length: 175 amino acids
Theoretical weight: 20.3 KDa
Source organism: synthetic construct
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 58%
Refinement method: NOESY back-calculation
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

A topological refactoring design strategy yields highly stable granulopoietic proteins.
Skokowa et al. (2022)
2 more

1 mention without citation

Design of novel granulopoietic proteins by topological rescaffolding.
Hernandez Alvarez et al. (2020)