› 6y41

X-ray diffraction
1.79Å resolution

Fibrinogen-like globe domain of human ANGPTL2

Released:
DOI: 10.2210/pdb6y41/pdb
PDB entry 6y41 coloured by chain, front view.
PDB entry 6y41 coloured by chain, side view.
PDB entry 6y41 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Coker JA, Krojer T, Mutisya JM, Arrowsmith CH, Bountra C, Midwood KS, Yue WW, Marsden BD, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193861 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Angiopoietin-related protein 2 Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Length: 227 amino acids
Theoretical weight: 26.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UKU9 (Residues: 269-493; Coverage: 48%)
Gene names: ANGPTL2, ARP2, UNQ170/PRO196
Sequence domains: Fibrinogen beta and gamma chains, C-terminal globular domain

Ligands and Environments

3 bound ligands:
Ligand CA 16 x CA
Ligand EDO 2 x EDO
Ligand TRS 2 x TRS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Unit cell:
a: 153.94Å b: 154.86Å c: 172.34Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.192 0.215
Expression system: Escherichia coli

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