› 6y5r

Electron Microscopy
3.76Å resolution

Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl

Released:
DOI: 10.2210/pdb6y5r/pdb
PDB entry 6y5r coloured by chain, front view.
PDB entry 6y5r coloured by chain, side view.
PDB entry 6y5r coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Chi G, Man H, Ebenhoch R, Reggiano G, Pike ACW, Wang D, McKinley G, Mukhopadhyay SMM, MacLean B, Chalk R, Moreau C, Snee M, Bohstedt T, Singh NK, Abrusci P, Arrowsmith CH, Bountra C, Edwards AM, Marsden BD, Burgess-Brown NA, DiMaio F, Duerr KL, Structural Genomics Consortium (SGC)
Related structures: EMD-10703

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193768 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Solute carrier family 12 member 6 Chains: A, B
Molecule details ›
Chains: A, B
Length: 1099 amino acids
Theoretical weight: 122.27 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9UHW9 (Residues: 71-78, 79-90, 91-1150; Coverage: 94%)
Gene names: KCC3, SLC12A6
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
1 bound ligand:
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.76Å
Relevant EMDB volumes: EMD-10703
Expression system: Homo sapiens

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