› 6yjj

X-ray diffraction
2.4Å resolution

Structure of CYRI-B (FAM49B) from Rhincodon typus (selenomethionine derivative)

Released:
DOI: 10.2210/pdb6yjj/pdb
PDB entry 6yjj coloured by chain, front view.
PDB entry 6yjj coloured by chain, side view.
PDB entry 6yjj coloured by chain, top view.
Source organism: Rhincodon typus
Primary publication:
Structure of CYRI-B (FAM49B), a key regulator of cellular actin assembly.
Kaplan E, Stone R, Hume PJ, Greene NP, Koronakis V
Acta Crystallogr D Struct Biol 76 1015-1024 (2020)
PMID: 33021503

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167882 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CYRI-B (FAM49B) Chain: A
Molecule details ›
Chain: A
Length: 325 amino acids
Theoretical weight: 37.38 KDa
Source organism: Rhincodon typus
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 10 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 40.4Å b: 72.82Å c: 107.32Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.205 0.242
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

The Application of CRISPR/Cas9 Technology for Cancer Immunotherapy: Current Status and Problems.
Wang et al. (2021)
6 other articles

1 mention without citation

Structure of CYRI-B (FAM49B), a key regulator of cellular actin assembly.
Kaplan et al. (2020)