› 6z1p

Electron Microscopy
3.7Å resolution

Structure of the mitochondrial ribosome from Tetrahymena thermophila

Released:
DOI: 10.2210/pdb6z1p/pdb
PDB entry 6z1p coloured by chain, front view.
PDB entry 6z1p coloured by chain, side view.
PDB entry 6z1p coloured by chain, top view.
Source organism: Tetrahymena thermophila SB210
Primary publication:
Ciliate mitoribosome illuminates evolutionary steps of mitochondrial translation.
Tobiasson V, Amunts A
Elife 9 (2020)
PMID: 32553108
Related structures: EMD-11032

Function and Biology Details

Reactions catalysed: 
3-hydroxy-2-methylpropanoyl-CoA + H(2)O = CoA + 3-hydroxy-2-methylpropanoate
Peptide-L-methionine + thioredoxin disulfide + H(2)O = peptide-L-methionine (R)-S-oxide + thioredoxin
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 99-mer (preferred)
PDBe Complex ID:
PDB-CPX-107437 (preferred)
Entry contents:
95 distinct polypeptide molecules
4 distinct RNA molecules
Macromolecules (99 distinct):
Large ribosomal subunit protein uL2 C-terminal domain-containing protein Chain: Ac
Molecule details ›
Chain: Ac
Length: 262 amino acids
Theoretical weight: 29.97 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951B6 (Residues: 1-262; Coverage: 100%)
Gene name: rpl2
Sequence domains: Ribosomal Proteins L2, C-terminal domain
Large ribosomal subunit protein uL3c Chain: Ad
Molecule details ›
Chain: Ad
Length: 439 amino acids
Theoretical weight: 49.88 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22HG3 (Residues: 1-439; Coverage: 100%)
Gene name: TTHERM_00637400
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein uL4m Chain: Ae
Molecule details ›
Chain: Ae
Length: 358 amino acids
Theoretical weight: 41.99 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7MGP2 (Residues: 1-358; Coverage: 100%)
Gene name: TTHERM_00564280
Sequence domains: Ribosomal protein L4/L1 family
Ymf69 Chain: Af
Molecule details ›
Chain: Af
Length: 68 amino acids
Theoretical weight: 8.39 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951A2 (Residues: 1-68; Coverage: 100%)
Gene name: ymf69
Ymf60 Chain: Ag
Molecule details ›
Chain: Ag
Length: 179 amino acids
Theoretical weight: 21.68 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951A9 (Residues: 1-179; Coverage: 100%)
Gene name: ymf60
bL7/L12m Chain: Ah
Molecule details ›
Chain: Ah
Length: 106 amino acids
Theoretical weight: 9.04 KDa
Source organism: Tetrahymena thermophila SB210
bL7/12m Chain: Ai
Molecule details ›
Chain: Ai
Length: 61 amino acids
Theoretical weight: 5.21 KDa
Source organism: Tetrahymena thermophila SB210
bL7/12m Chain: Aj
Molecule details ›
Chain: Aj
Length: 69 amino acids
Theoretical weight: 5.89 KDa
Source organism: Tetrahymena thermophila SB210
Large ribosomal subunit protein bL12 C-terminal domain-containing protein Chain: Ak
Molecule details ›
Chain: Ak
Length: 105 amino acids
Theoretical weight: 12.39 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q24IM4 (Residues: 61-163; Coverage: 37%)
Gene name: TTHERM_00918510
Ribosomal protein L9 domain-containing protein Chain: Al
Molecule details ›
Chain: Al
Length: 223 amino acids
Theoretical weight: 26.23 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q24C33 (Residues: 1-223; Coverage: 100%)
Gene name: TTHERM_00697430
Sequence domains: Ribosomal protein L9, N-terminal domain
Ymf74 Chain: Am
Molecule details ›
Chain: Am
Length: 166 amino acids
Theoretical weight: 19.96 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951B5 (Residues: 1-157; Coverage: 100%)
Gene name: ymf74
Large ribosomal subunit protein uL11m Chain: An
Molecule details ›
Chain: An
Length: 158 amino acids
Theoretical weight: 17.82 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: W7XH77 (Residues: 1-158; Coverage: 100%)
Gene name: TTHERM_000585349
Sequence domains:
50S ribosomal protein L13 Chain: Ao
Molecule details ›
Chain: Ao
Length: 391 amino acids
Theoretical weight: 45.1 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: W7X626 (Residues: 1-391; Coverage: 100%)
Gene name: TTHERM_001207659
Sequence domains: Ribosomal protein L13
Ribosomal protein L14 Chain: Ap
Molecule details ›
Chain: Ap
Length: 119 amino acids
Theoretical weight: 13.61 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q950Y1 (Residues: 1-119; Coverage: 100%)
Gene name: rpl14
Sequence domains: Ribosomal protein L14p/L23e
Large ribosomal subunit protein uL15/eL18 domain-containing protein Chain: Aq
Molecule details ›
Chain: Aq
Length: 305 amino acids
Theoretical weight: 34.67 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7MF78 (Residues: 1-305; Coverage: 100%)
Gene name: TTHERM_00136240
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
Ribosomal protein L16 Chain: Ar
Molecule details ›
Chain: Ar
Length: 143 amino acids
Theoretical weight: 17.46 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951A0 (Residues: 1-143; Coverage: 100%)
Gene name: rpl16
Sequence domains: Ribosomal protein L16p/L10e
50S ribosomal protein L17 Chain: As
Molecule details ›
Chain: As
Length: 237 amino acids
Theoretical weight: 27.71 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: A4VE95 (Residues: 1-237; Coverage: 100%)
Gene name: TTHERM_00106969
Sequence domains: Ribosomal protein L17
Ribosomal protein L19 Chain: At
Molecule details ›
Chain: At
Length: 242 amino acids
Theoretical weight: 28.83 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7M2I9 (Residues: 1-242; Coverage: 100%)
Gene name: TTHERM_00408950
50S ribosomal protein L20 Chain: Au
Molecule details ›
Chain: Au
Length: 170 amino acids
Theoretical weight: 20.23 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q235I3 (Residues: 1-170; Coverage: 100%)
Gene name: TTHERM_01034460
Sequence domains: Ribosomal protein L20
Large ribosomal subunit protein bL21m Chain: Av
Molecule details ›
Chain: Av
Length: 235 amino acids
Theoretical weight: 27.63 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7LVD3 (Residues: 1-235; Coverage: 100%)
Gene name: TTHERM_00280990
Sequence domains: Ribosomal prokaryotic L21 protein
Large ribosomal subunit protein uL22m Chain: Aw
Molecule details ›
Chain: Aw
Length: 364 amino acids
Theoretical weight: 42.83 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q23CT9 (Residues: 1-364; Coverage: 100%)
Gene name: TTHERM_00052510
Sequence domains: Ribosomal protein L22p/L17e
Large ribosomal subunit protein uL23m Chain: Ax
Molecule details ›
Chain: Ax
Length: 138 amino acids
Theoretical weight: 16.21 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22EY1 (Residues: 1-138; Coverage: 100%)
Gene name: TTHERM_00822340
Sequence domains: Ribosomal protein L23
Large ribosomal subunit protein uL24c Chain: Ay
Molecule details ›
Chain: Ay
Length: 234 amino acids
Theoretical weight: 26.65 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q24C34 (Residues: 1-234; Coverage: 100%)
Gene name: TTHERM_00697420
Sequence domains:
bL25m Chain: Az
Molecule details ›
Chain: Az
Length: 321 amino acids
Theoretical weight: 37.21 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7LVZ3 (Residues: 1-321; Coverage: 100%)
Gene name: TTHERM_00220590
50S ribosomal protein L27 Chain: AA
Molecule details ›
Chain: AA
Length: 237 amino acids
Theoretical weight: 27.38 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7M068 (Residues: 1-237; Coverage: 100%)
Gene name: TTHERM_00419850
Sequence domains: Ribosomal L27 protein
Ribosomal protein L28 Chain: AB
Molecule details ›
Chain: AB
Length: 289 amino acids
Theoretical weight: 35.04 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7LU83 (Residues: 1-289; Coverage: 100%)
Gene name: TTHERM_00140980
Sequence domains: Ribosomal L28 family
Large ribosomal subunit protein uL29m Chain: AC
Molecule details ›
Chain: AC
Length: 307 amino acids
Theoretical weight: 36.61 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22W36 (Residues: 1-307; Coverage: 100%)
Gene name: TTHERM_00160960
Sequence domains: Mitochondrial 39-S ribosomal protein L47 (MRP-L47)
bL32m Chain: AD
Molecule details ›
Chain: AD
Length: 36 amino acids
Theoretical weight: 3.08 KDa
Source organism: Tetrahymena thermophila SB210
50S ribosomal protein L33 Chain: AE
Molecule details ›
Chain: AE
Length: 64 amino acids
Theoretical weight: 7.24 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22L35 (Residues: 1-64; Coverage: 100%)
Gene name: TTHERM_01013180
Sequence domains: Ribosomal protein L33
50S ribosomal protein L35 Chain: AF
Molecule details ›
Chain: AF
Length: 164 amino acids
Theoretical weight: 19.55 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7M803 (Residues: 1-164; Coverage: 100%)
Gene name: TTHERM_00189300
Sequence domains: Ribosomal protein L35
Ribosomal protein Chain: AG
Molecule details ›
Chain: AG
Length: 93 amino acids
Theoretical weight: 11.12 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: W7XH61 (Residues: 1-93; Coverage: 100%)
Gene name: TTHERM_000446568
Sequence domains: Ribosomal protein L36
mL40 Chain: AH
Molecule details ›
Chain: AH
Length: 199 amino acids
Theoretical weight: 23.72 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7LT48 (Residues: 1-199; Coverage: 100%)
Gene name: TTHERM_00716190
Ribosomal protein L27 Chain: AI
Molecule details ›
Chain: AI
Length: 155 amino acids
Theoretical weight: 18.51 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7MG40 (Residues: 1-155; Coverage: 100%)
Gene name: TTHERM_00316160
Sequence domains: Mitochondrial ribosomal protein L27
Large ribosomal subunit protein mL43 Chain: AJ
Molecule details ›
Chain: AJ
Length: 179 amino acids
Theoretical weight: 21.16 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22RG0 (Residues: 1-179; Coverage: 100%)
Gene name: TTHERM_00016270
Sequence domains: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
39S ribosomal protein L46, mitochondrial Chain: AK
Molecule details ›
Chain: AK
Length: 309 amino acids
Theoretical weight: 36.86 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7LWM6 (Residues: 1-309; Coverage: 100%)
Gene name: TTHERM_00558550
Large ribosomal subunit protein mL49 Chain: AL
Molecule details ›
Chain: AL
Length: 145 amino acids
Theoretical weight: 16.83 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7MAF1 (Residues: 1-145; Coverage: 100%)
Gene name: TTHERM_00616380
Sequence domains: Mitochondrial large subunit ribosomal protein (Img2)
mL53 Chain: AM
Molecule details ›
Chain: AM
Length: 184 amino acids
Theoretical weight: 22 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22KC0 (Residues: 1-184; Coverage: 100%)
Gene name: TTHERM_00313610
mL54 Chain: AN
Molecule details ›
Chain: AN
Length: 158 amino acids
Theoretical weight: 18.24 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7MI39 (Residues: 1-158; Coverage: 100%)
Gene name: TTHERM_00455100
Sequence domains: Mitochondrial ribosomal protein L37
mL64 Chain: AO
Molecule details ›
Chain: AO
Length: 155 amino acids
Theoretical weight: 18.19 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q23ZH7 (Residues: 1-155; Coverage: 100%)
Gene name: TTHERM_00785870
mL101 Chain: AP
Molecule details ›
Chain: AP
Length: 386 amino acids
Theoretical weight: 45.71 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7M3V9 (Residues: 1-386; Coverage: 100%)
Gene name: TTHERM_00614680
mL102 Chain: AQ
Molecule details ›
Chain: AQ
Length: 109 amino acids
Theoretical weight: 12.87 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: W7WYR3 (Residues: 1-109; Coverage: 100%)
Gene name: TTHERM_000659131
mL103 Chain: AR
Molecule details ›
Chain: AR
Length: 348 amino acids
Theoretical weight: 41.56 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7MKV5 (Residues: 1-348; Coverage: 100%)
Gene name: TTHERM_00220600
mL104 Chain: AS
Molecule details ›
Chain: AS
Length: 764 amino acids
Theoretical weight: 90.01 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7LTP6 (Residues: 1-763; Coverage: 100%)
Gene name: TTHERM_00420290
Signal recognition particle SRP54 subunit M-domain domain-containing protein Chain: AT
Molecule details ›
Chain: AT
Length: 299 amino acids
Theoretical weight: 35.49 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: W7XFS0 (Residues: 1-299; Coverage: 100%)
Gene name: TTHERM_000931898
Sequence domains: Signal peptide binding domain
mL106 Chain: AU
Molecule details ›
Chain: AU
Length: 499 amino acids
Theoretical weight: 57.79 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q23Q81 (Residues: 1-499; Coverage: 100%)
Gene name: TTHERM_00582070
Iron-binding zinc finger CDGSH type domain-containing protein Chain: AV
Molecule details ›
Chain: AV
Length: 160 amino acids
Theoretical weight: 18.46 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22HE3 (Residues: 1-160; Coverage: 100%)
Gene name: TTHERM_00637600
Sequence domains: Iron-binding zinc finger CDGSH type
Ymf73 Chain: Bc
Molecule details ›
Chain: Bc
Length: 159 amino acids
Theoretical weight: 19.46 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q950X8 (Residues: 1-159; Coverage: 100%)
Gene name: ymf73
Ymf64 Chain: Bd
Molecule details ›
Chain: Bd
Length: 330 amino acids
Theoretical weight: 40.1 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951A8 (Residues: 1-330; Coverage: 100%)
Gene name: ymf64
Ymf76 Chain: Be
Molecule details ›
Chain: Be
Length: 405 amino acids
Theoretical weight: 50.83 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951C0 (Residues: 1-405; Coverage: 100%)
Gene name: ymf76
S5 DRBM domain-containing protein Chain: Bf
Molecule details ›
Chain: Bf
Length: 351 amino acids
Theoretical weight: 40.87 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7M4M7 (Residues: 1-351; Coverage: 100%)
Gene name: TTHERM_00497450
Sequence domains: Ribosomal protein S5, N-terminal domain
Ribosomal protein S6 Chain: Bg
Molecule details ›
Chain: Bg
Length: 141 amino acids
Theoretical weight: 15.97 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7MHS2 (Residues: 1-141; Coverage: 100%)
Gene name: TTHERM_00535550
Sequence domains: Ribosomal protein S6
Ymf63 Chain: Bh
Molecule details ›
Chain: Bh
Length: 276 amino acids
Theoretical weight: 33.56 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951A4 (Residues: 1-276; Coverage: 100%)
Gene name: ymf63
Ribosomal protein S9 Chain: Bi
Molecule details ›
Chain: Bi
Length: 737 amino acids
Theoretical weight: 87.31 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7M4A2 (Residues: 1-737; Coverage: 100%)
Gene name: TTHERM_00670170
Sequence domains: Ribosomal protein S9/S16
Ymf59 Chain: Bj
Molecule details ›
Chain: Bj
Length: 152 amino acids
Theoretical weight: 18.39 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951A1 (Residues: 1-152; Coverage: 100%)
Gene name: ymf59
Ymf61 Chain: Bk
Molecule details ›
Chain: Bk
Length: 238 amino acids
Theoretical weight: 29.05 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q950Z8 (Residues: 1-238; Coverage: 100%)
Gene name: ymf61
Ribosomal protein S12 Chain: Bl
Molecule details ›
Chain: Bl
Length: 133 amino acids
Theoretical weight: 15.3 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951B3 (Residues: 1-133; Coverage: 100%)
Gene name: rps12
Sequence domains: Ribosomal protein S12/S23
Ribosomal protein S13 Chain: Bm
Molecule details ›
Chain: Bm
Length: 276 amino acids
Theoretical weight: 33.44 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951B9 (Residues: 1-276; Coverage: 100%)
Gene name: rps13
Sequence domains: Ribosomal protein S13/S18
Ribosomal protein S14 Chain: Bn
Molecule details ›
Chain: Bn
Length: 101 amino acids
Theoretical weight: 12.31 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951B0 (Residues: 1-101; Coverage: 100%)
Gene name: rps14
30S ribosomal protein S15 Chain: Bo
Molecule details ›
Chain: Bo
Length: 196 amino acids
Theoretical weight: 23.14 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22WF3 (Residues: 1-196; Coverage: 100%)
Gene name: TTHERM_00157810
Sequence domains: Ribosomal protein S15
30S ribosomal protein S16 Chain: Bp
Molecule details ›
Chain: Bp
Length: 437 amino acids
Theoretical weight: 52.07 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7M3F6 (Residues: 1-437; Coverage: 100%)
Gene name: TTHERM_00444330
Sequence domains: Ribosomal protein S16
30S ribosomal protein S17 Chain: Bq
Molecule details ›
Chain: Bq
Length: 182 amino acids
Theoretical weight: 21.43 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7M6C7 (Residues: 2-180; Coverage: 87%)
Gene name: TTHERM_00585250
Sequence domains: Ribosomal protein S17
Ribosomal protein S18 Chain: Br
Molecule details ›
Chain: Br
Length: 549 amino acids
Theoretical weight: 63.88 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q23K82 (Residues: 1-549; Coverage: 100%)
Gene name: TTHERM_00194530
Sequence domains: Ribosomal protein S18
Ribosomal protein S19 Chain: Bs
Molecule details ›
Chain: Bs
Length: 98 amino acids
Theoretical weight: 11.62 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951B7 (Residues: 1-98; Coverage: 100%)
Gene name: rps19
Sequence domains: Ribosomal protein S19
bS21m Chain: Bt
Molecule details ›
Chain: Bt
Length: 102 amino acids
Theoretical weight: 12.34 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22BA0 (Residues: 1-102; Coverage: 100%)
Gene name: TTHERM_01108550
mS23 Chain: Bu
Molecule details ›
Chain: Bu
Length: 567 amino acids
Theoretical weight: 63.64 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q23YQ0 (Residues: 1-583; Coverage: 84%)
Gene name: TTHERM_01207720
mS26 Chain: Bv
Molecule details ›
Chain: Bv
Length: 579 amino acids
Theoretical weight: 69.41 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7M0P0 (Residues: 1-579; Coverage: 100%)
Gene name: TTHERM_00561490
Small ribosomal subunit protein mS29 Chain: Bw
Molecule details ›
Chain: Bw
Length: 703 amino acids
Theoretical weight: 83.46 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22RT0 (Residues: 1-703; Coverage: 100%)
Gene name: TTHERM_00013070
Sequence domains: Mitochondrial ribosomal death-associated protein 3
mS31 Chain: Bx
Molecule details ›
Chain: Bx
Length: 719 amino acids
Theoretical weight: 83.82 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q23UD3 (Residues: 1-719; Coverage: 100%)
Gene name: TTHERM_00797930
mS33 Chain: By
Molecule details ›
Chain: By
Length: 132 amino acids
Theoretical weight: 15.14 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7LW04 (Residues: 1-132; Coverage: 100%)
Gene name: TTHERM_00221170
mS34 Chain: Bz
Molecule details ›
Chain: Bz
Length: 147 amino acids
Theoretical weight: 16.76 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7LWU8 (Residues: 1-147; Coverage: 100%)
Gene name: TTHERM_00492510
Small ribosomal subunit protein mS35 mitochondrial conserved domain-containing protein Chain: BA
Molecule details ›
Chain: BA
Length: 149 amino acids
Theoretical weight: 17.98 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q23K64 (Residues: 1-149; Coverage: 100%)
Gene name: TTHERM_00194710
Sequence domains: Mitochondrial ribosomal subunit protein
mS37 Chain: BB
Molecule details ›
Chain: BB
Length: 112 amino acids
Theoretical weight: 13.5 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7MMM6 (Residues: 1-112; Coverage: 100%)
Gene name: TTHERM_00780710
mS38 Chain: BC
Molecule details ›
Chain: BC
Length: 37 amino acids
Theoretical weight: 3.17 KDa
Source organism: Tetrahymena thermophila SB210
Small ribosomal subunit protein mS41 Chain: BD
Molecule details ›
Chain: BD
Length: 130 amino acids
Theoretical weight: 15.21 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22FZ4 (Residues: 1-130; Coverage: 100%)
Gene name: TTHERM_00721630
Sequence domains: IGR protein motif
mS45 Chain: BE
Molecule details ›
Chain: BE
Length: 464 amino acids
Theoretical weight: 54.96 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q23DN6 (Residues: 1-464; Coverage: 100%)
Gene name: TTHERM_00046550
mS75 Chain: BF
Molecule details ›
Chain: BF
Length: 23 amino acids
Theoretical weight: 1.98 KDa
Source organism: Tetrahymena thermophila SB210
mS76 Chain: BG
Molecule details ›
Chain: BG
Length: 182 amino acids
Theoretical weight: 21.74 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q24G80 (Residues: 1-182; Coverage: 100%)
Gene name: TTHERM_01212860
mS77 Chain: BH
Molecule details ›
Chain: BH
Length: 63 amino acids
Theoretical weight: 5.38 KDa
Source organism: Tetrahymena thermophila SB210
3-hydroxyisobutyryl-CoA hydrolase Chain: BI
Molecule details ›
Chain: BI
Length: 1451 amino acids
Theoretical weight: 171.47 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22P47 (Residues: 1-1451; Coverage: 100%)
Gene name: TTHERM_00414440
Sequence domains: Enoyl-CoA hydratase/isomerase
mS78 Chain: BJ
Molecule details ›
Chain: BJ
Length: 1539 amino acids
Theoretical weight: 179.26 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7M7B1 (Residues: 1-1539; Coverage: 100%)
Gene name: TTHERM_00145010
mS79 Chain: BK
Molecule details ›
Chain: BK
Length: 267 amino acids
Theoretical weight: 30.23 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q23DG3 (Residues: 1-267; Coverage: 100%)
Gene name: TTHERM_00047280
peptide-methionine (R)-S-oxide reductase Chain: BL
Molecule details ›
Chain: BL
Length: 310 amino acids
Theoretical weight: 36.65 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22W57 (Residues: 1-310; Coverage: 100%)
Gene name: TTHERM_00160750
Sequence domains: SelR domain
mS81 Chain: BM
Molecule details ›
Chain: BM
Length: 355 amino acids
Theoretical weight: 42.32 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q24E31 (Residues: 1-355; Coverage: 100%)
Gene name: TTHERM_00853090
EF-hand domain-containing protein Chain: BN
Molecule details ›
Chain: BN
Length: 283 amino acids
Theoretical weight: 33.6 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22GF7 (Residues: 1-283; Coverage: 100%)
Gene name: TTHERM_00703660
PARP alpha-helical domain-containing protein Chain: BO
Molecule details ›
Chain: BO
Length: 142 amino acids
Theoretical weight: 13.27 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22N51 (Residues: 107-142; Coverage: 3%)
Gene name: TTHERM_00214830
mS84,mS84 Chain: BP
Molecule details ›
Chain: BP
Length: 100 amino acids
Theoretical weight: 10.45 KDa
Source organism: Tetrahymena thermophila SB210
RRM domain-containing protein Chain: BQ
Molecule details ›
Chain: BQ
Length: 1032 amino acids
Theoretical weight: 120.91 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22UP3 (Residues: 1-1032; Coverage: 100%)
Gene name: TTHERM_00550810
Iron donor protein CyaY Chain: BR
Molecule details ›
Chain: BR
Length: 143 amino acids
Theoretical weight: 16.79 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q240K3 (Residues: 1-143; Coverage: 100%)
Gene name: TTHERM_00989460
Sequence domains: Frataxin-like domain
mS87 Chain: BS
Molecule details ›
Chain: BS
Length: 1086 amino acids
Theoretical weight: 127.22 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: A4VCP7 (Residues: 1-1086; Coverage: 100%)
Gene name: TTHERM_00647339
mS88 Chain: BT
Molecule details ›
Chain: BT
Length: 297 amino acids
Theoretical weight: 25.24 KDa
Source organism: Tetrahymena thermophila SB210
mS89 Chain: BU
Molecule details ›
Chain: BU
Length: 439 amino acids
Theoretical weight: 51.87 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q22EB6 (Residues: 1-439; Coverage: 100%)
Gene name: TTHERM_00835120
mS90 Chain: BV
Molecule details ›
Chain: BV
Length: 310 amino acids
Theoretical weight: 33.26 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q24HL0 (Residues: 79-302; Coverage: 56%)
Gene name: TTHERM_01057750
mS91 Chain: BW
Molecule details ›
Chain: BW
Length: 285 amino acids
Theoretical weight: 24.27 KDa
Source organism: Tetrahymena thermophila SB210
Ribosomal protein S3 Chain: BX
Molecule details ›
Chain: BX
Length: 151 amino acids
Theoretical weight: 18.51 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: Q951B8 (Residues: 1-151; Coverage: 100%)
Gene name: rps3
mTERF protein Chain: BY
Molecule details ›
Chain: BY
Length: 327 amino acids
Theoretical weight: 37.25 KDa
Source organism: Tetrahymena thermophila SB210
UniProt:
  • Canonical: I7LUK3 (Residues: 96-387; Coverage: 71%)
Gene name: TTHERM_00522240
Sequence domains: mTERF
LSU rRNA_1 Chain: Aa
Molecule details ›
Chain: Aa
Length: 278 nucleotides
Theoretical weight: 89.37 KDa
LSU rRNA_2 Chain: Ab
Molecule details ›
Chain: Ab
Length: 2314 nucleotides
Theoretical weight: 743.59 KDa
Sequence domains: Bacterial large subunit ribosomal RNA
SSU rRNA_1 Chain: Ba
Molecule details ›
Chain: Ba
Length: 196 nucleotides
Theoretical weight: 62.98 KDa
SSU rRNA_2 Chain: Bb
Molecule details ›
Chain: Bb
Length: 1395 nucleotides
Theoretical weight: 448.29 KDa
Sequence domains: Bacterial small subunit ribosomal RNA

Ligands and Environments

4 bound ligands:
Ligand MG 393 x MG
Ligand ZN 2 x ZN
Ligand FES 2 x FES
Ligand ATP 1 x ATP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-11032

Quick links

Citations

2 review citations

Mechanisms and regulation of protein synthesis in mitochondria.
Kummer et al. (2021)
1 more

4 mentions without citation

Ciliate mitoribosome illuminates evolutionary steps of mitochondrial translation.
Tobiasson et al. (2020)
3 more