Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
DNA-dependent protein kinase complex and DNA (preferred)
PDBe Complex ID:
PDB-CPX-121013 (preferred)
Entry contents:
3 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (5 distinct):
DNA-dependent protein kinase catalytic subunit
Molecule details ›
Chain: A
Length: 4156 amino acids
Theoretical weight: 472.06 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 4156 amino acids
Theoretical weight: 472.06 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P78527 (Residues: 1-4128; Coverage: 100%)
Sequence domains:
X-ray repair cross-complementing protein 6
Molecule details ›
Chain: B
Length: 609 amino acids
Theoretical weight: 69.95 KDa
Source organism: Homo sapiens
Expression system: Insect cell expression vector pTIE1
UniProt:
Sequence domains:
Length: 609 amino acids
Theoretical weight: 69.95 KDa
Source organism: Homo sapiens
Expression system: Insect cell expression vector pTIE1
UniProt:
- Canonical: P12956 (Residues: 1-609; Coverage: 100%)
Sequence domains:
X-ray repair cross-complementing protein 5
Molecule details ›
Chain: C
Length: 732 amino acids
Theoretical weight: 82.81 KDa
Source organism: Homo sapiens
Expression system: Insect cell expression vector pTIE1
UniProt:
Sequence domains:
Length: 732 amino acids
Theoretical weight: 82.81 KDa
Source organism: Homo sapiens
Expression system: Insect cell expression vector pTIE1
UniProt:
- Canonical: P13010 (Residues: 1-732; Coverage: 100%)
Sequence domains:
