› 7asu

X-ray diffraction
2.23Å resolution

Crystal structure of tWHD1 of Rpc5 subunit of human RNA Polymerase III

Released:
DOI: 10.2210/pdb7asu/pdb
PDB entry 7asu coloured by chain, front view.
PDB entry 7asu coloured by chain, side view.
PDB entry 7asu coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of human RNA polymerase III.
Ramsay EP, Abascal-Palacios G, Daiß JL, King H, Gouge J, Pilsl M, Beuron F, Morris E, Gunkel P, Engel C, Vannini A
Nat Commun 11 6409 (2020)
PMID: 33335104

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192640 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA-directed RNA polymerase III subunit RPC5 Chain: A
Molecule details ›
Chain: A
Length: 708 amino acids
Theoretical weight: 80 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NVU0 (Residues: 1-708; Coverage: 100%)
Gene names: KIAA1452, POLR3E
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 4 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04, DIAMOND BEAMLINE I03
Spacegroup: P6122
Unit cell:
a: 56.3Å b: 56.3Å c: 275.88Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.18 0.18 0.22
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Battle Royale: Innate Recognition of Poxviruses and Viral Immune Evasion.
Yu et al. (2021)
11 more