Protein Data Bank in Europe

Chain: A
Length: 764 amino acids
Theoretical weight: 87.2 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:

• Canonical: Q15910 (Residues: 1-297, 298-486, 487-746; Coverage: 100%)

Gene names: EZH2, KMT6
Sequence domains:

• WD repeat binding protein EZH2
• Polycomb repressive complex 2 tri-helical domain
• Ezh2, MCSS domain
• CXC domain
• SET domain

Chain: C
Length: 739 amino acids
Theoretical weight: 83.18 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:

• Canonical: Q15022 (Residues: 1-739; Coverage: 100%)

Gene names: CHET9, JJAZ1, KIAA0160, SUZ12
Sequence domains: VEFS-Box of polycomb protein

Chains: D, H
Length: 135 amino acids
Theoretical weight: 15.3 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:

• Canonical: P84233 (Residues: 2-136; Coverage: 99%)

Sequence domains: Core histone H2A/H2B/H3/H4

Chains: E, I
Length: 102 amino acids
Theoretical weight: 11.26 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:

• Canonical: P62799 (Residues: 2-103; Coverage: 99%)

Sequence domains: Centromere kinetochore component CENP-T histone fold

Chains: F, J
Length: 129 amino acids
Theoretical weight: 13.98 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:

• Canonical: P06897 (Residues: 2-130; Coverage: 99%)

Sequence domains:

• Core histone H2A/H2B/H3/H4
• C-terminus of histone H2A

Chains: G, K
Length: 122 amino acids
Theoretical weight: 13.52 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:

• Canonical: P02281 (Residues: 5-126; Coverage: 97%)

Sequence domains: Core histone H2A/H2B/H3/H4

Chain: T
Length: 156 nucleotides
Theoretical weight: 47.9 KDa

Chain: U
Length: 156 nucleotides
Theoretical weight: 48.4 KDa