7jm7

Electron Microscopy
2.82Å resolution

Structure of human CLC-7/OSTM1 complex

Released:
Source organism: Homo sapiens
Related structures: EMD-22389

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-156418 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Osteopetrosis-associated transmembrane protein 1 Chains: B, D
Molecule details ›
Chains: B, D
Length: 334 amino acids
Theoretical weight: 37.29 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q86WC4 (Residues: 1-334; Coverage: 100%)
Gene names: GL, HSPC019, OSTM1, UNQ6098/PRO21201
Sequence domains: Osteopetrosis-associated transmembrane protein 1 precursor
H(+)/Cl(-) exchange transporter 7 Chains: A, C
Molecule details ›
Chains: A, C
Length: 805 amino acids
Theoretical weight: 88.77 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P51798 (Residues: 1-805; Coverage: 100%)
Gene name: CLCN7
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.82Å
Relevant EMDB volumes: EMD-22389
Expression system: Homo sapiens