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Adam-Vizi V
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Szabo E
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Torocsik B
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Center for Structural Genomics of Infectious Diseases (CSGID)
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Kamiya N
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Lima CD
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Minasov G
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Brautigam CA
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Chuang DT
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Chuang JL
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Dubrovska I
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Hol WG
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RIKEN Structural Genomics/Proteomics Initiative (RSGI)
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Newman DK
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DLD
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lpd
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PA14_43970
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A2J79_001385
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A5U30_000356
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ABE91_003360
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ACU57_15945
(1)
AWP47_05280
(1)
B6R15_000279
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B6R31_002519
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BANRA_00587
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BANRA_02325
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BCB93_001533
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BD94_2540
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C6669_04550
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C719_003153
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C9160_13845
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C9194_10960
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CF22_002815
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CG702_01665
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CIG67_21415
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CR538_20930
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DD762_00810
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F9461_05080
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F9B07_03785
(1)
FGAF848_50510
(1)
FIJ20_10985
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Representative Structures
Representative Structures
Entries
Macromolecules
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Entries 1 to 10 of 52
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Cryo-EM structure of Mtb Lpd bound to inhibitor complex with 2-((2-cyano-N,5-dimethyl-1H-indole)-7-sulfonamido)-N-(4-(oxetan-3-yl)-3,4-dihydro-2H-benzo[b] [1,4]oxazin-7-yl)acetamide
Kochanczyk T, Arango N, Lima CD
Not published
Source organism: Mycobacterium tuberculosis
Assembly composition: protein only structure
Assembly name:
Dihydrolipoyl dehydrogenase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-161554 (Preferred)
search this ID

Co-crystal structure of optimized analog TDI-13537 provided new insights into the potency determinants of the sulfonamide inhibitor series
Dementiev AA, Michino M, Vendome J, Ginn J, Bryk R, Olland A
ACS Bio Med Chem Au
(2023)
[PMID: 38144256 ]
Source organism: Mycobacterium tuberculosis
Assembly composition: protein only structure
Assembly name:
Dihydrolipoyl dehydrogenase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-161554 (Preferred)
search this ID

1.72 Angstrom Resolution Crystal Structure of 2-Oxoglutarate Dehydrogenase Complex Subunit Dihydrolipoamide Dehydrogenase from Bordetella pertussis in Complex with FAD
Minasov G, Wawrzak Z, Skarina T, McChesney C, Grimshaw S, Savchenko A, Anderson WF, Center for Structural Genomics of Infectious Diseases (CSGID)
To be published
Source organism: Bordetella pertussis Tohama I
Assembly composition: protein only structure
Assembly name:
Dihydrolipoyl dehydrogenase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-182092 (Preferred)
search this ID

Structure of Mtb Lpd bound to SL827
Lima CD
Biochemistry
(2013)
[PMID: 24251446 ]
Source organism: Mycobacterium tuberculosis
Assembly composition: protein only structure
Assembly name:
Dihydrolipoyl dehydrogenase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-161554 (Preferred)
search this ID

Crystal structure of a dihydrolipoamide dehydrogenase from Sinorhizobium meliloti 1021
Kumaran D, Chamala S, Evans B, Foti R, Gizzi A, Hillerich B, Kar A, LaFleur J, Seidel R, Villigas G, Zencheck W, Almo SC, Swaminathan S, New York Structural Genomics Research Consortium (NYSGRC)
To be published
Source organism: Sinorhizobium meliloti 1021
Assembly composition: protein only structure
Assembly name:
Dihydrolipoyl dehydrogenase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-187877 (Preferred)
search this ID

2.5 Angstrom Resolution Crystal Structure of Dihydrolipoyl Dehydrogenase from Pseudomonas putida in Complex with FAD.
Minasov G, Wawrzak Z, Shuvalova L, Kiryukhina O, Dubrovska I, Grimshaw S, Kwon K, Anderson WF, Center for Structural Genomics of Infectious Diseases (CSGID)
To be published
Source organism: Pseudomonas putida KT2440
Assembly composition: protein only structure
Assembly name:
Dihydrolipoyl dehydrogenase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-183459 (Preferred)
search this ID

Crystal structure of the D444V disease-causing mutant of the human dihydrolipoamide dehydrogenase
Szabo E, Mizsei R, Zambo Z, Torocsik B, Weiss MS, Adam-Vizi V, Ambrus A
Free Radic Biol Med
(2018)
[PMID: 29908278 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Dihydrolipoyl dehydrogenase, mitochondrial
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-140717 (Preferred)
search this ID
Crystal structure of the R460G disease-causing mutant of the human dihydrolipoamide dehydrogenase.
Ambrus A, Szabo E, Weichsel A, Bui D, Wilk P, Torocsik B, Weiss MS, Montfort WR, Jordan F, Adam-Vizi V
To be published
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Dihydrolipoyl dehydrogenase, mitochondrial
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-140717 (Preferred)
search this ID
1.83 Angstrom Resolution Crystal Structure of Dihydrolipoyl Dehydrogenase from Pseudomonas putida in Complex with FAD and Adenosine-5'-monophosphate.
Minasov G, Shuvalova L, Kiryukhina O, Dubrovska I, Grimshaw S, Kwon K, Anderson WF, Satchell KJF, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)
To be published
Source organism: Pseudomonas putida KT2440
Assembly composition: protein only structure
Assembly name:
Dihydrolipoyl dehydrogenase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-183459 (Preferred)
search this ID

Dihydrolipoamide dehydrogenase (LpdG) from Pseudomonas aeruginosa
Glasser NR, Wang BX, Hoy JA, Newman DK
J Biol Chem
(2017)
[PMID: 28174304 ]
Source organism: Pseudomonas aeruginosa UCBPP-PA14
Assembly composition: protein only structure
Assembly name:
Dihydrolipoyl dehydrogenase
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-191332 (Preferred)
search this ID

...
Entries 1 to 10 of 52