› 143d

Solution NMR

SOLUTION STRUCTURE OF THE HUMAN TELOMERIC REPEAT D(AG3[T2AG3]3) OF THE G-QUADRUPLEX

Released:
DOI: 10.2210/pdb143d/pdb
PDB entry 143d coloured by chain, ensemble of 6 models, front view.
PDB entry 143d coloured by chain, ensemble of 6 models, side view.
PDB entry 143d coloured by chain, ensemble of 6 models, top view.
Source organism: synthetic construct
Primary publication:
Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex.
Wang Y, Patel DJ
Structure 1 263-82 (1993)
PMID: 8081740

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113333 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3') Chain: A
Molecule details ›
Chain: A
Length: 22 nucleotides
Theoretical weight: 6.98 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY, MOLECULAR DYNAMICS
Expression system: Not provided

Quick links

Citations

79 review citations

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
Balasubramanian et al. (2011)
78 more

103 mentions without citation

Quadruplex DNA: sequence, topology and structure.
Burge et al. (2006)
102 more