› 178d

X-ray diffraction
2.5Å resolution

CRYSTAL STRUCTURE OF A DNA DUPLEX CONTAINING 8-HYDROXYDEOXYGUANINE.ADENINE BASE-PAIRS

Released:
DOI: 10.2210/pdb178d/pdb
PDB entry 178d coloured by chain, front view.
PDB entry 178d coloured by chain, side view.
PDB entry 178d coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystal structure of a DNA duplex containing 8-hydroxydeoxyguanine-adenine base pairs.
McAuley-Hecht KE, Leonard GA, Gibson NJ, Thomson JB, Watson WP, Hunter WN, Brown T
Biochemistry 33 10266-70 (1994)
PMID: 8068665

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113356 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*(8OG)P*GP*CP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 12 nucleotides
Theoretical weight: 3.7 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand 8OG 2 x 8OG

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 24.67Å b: 40.49Å c: 65.14Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 not available not available
Expression system: Not provided

Quick links

Citations

22 review citations

Reactions of oxyl radicals with DNA.
Breen et al. (1995)
21 more

9 mentions without citation

Shape-controlled synthesis of metal nanocrystals: simple chemistry meets complex physics?
Xia et al. (2009)
8 more