› 1uoj

X-ray diffraction
2.4Å resolution

CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN 1 IN THE CALCIUM-FREE STATE

Released:
DOI: 10.2210/pdb1uoj/pdb
PDB entry 1uoj coloured by chain, front view.
PDB entry 1uoj coloured by chain, side view.
PDB entry 1uoj coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
Structural basis of calcium and galactose recognition by the lectin PA-IL of Pseudomonas aeruginosa.
Cioci G, Mitchell EP, Gautier C, Wimmerová M, Sudakevitz D, Pérez S, Gilboa-Garber N, Imberty A
FEBS Lett 555 297-301 (2003)
PMID: 14644431

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170133 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PA-I galactophilic lectin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 121 amino acids
Theoretical weight: 12.77 KDa
Source organism: Pseudomonas aeruginosa
UniProt:
  • Canonical: Q05097 (Residues: 2-122; Coverage: 99%)
Gene names: PA2570, lecA, pa1L
Sequence domains: PA-IL-like protein
Structure domains: Galactose-binding lectin

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 49.675Å b: 51.464Å c: 166.787Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.183 0.263

Quick links

Citations

12 review citations

Multivalent glycoconjugates as anti-pathogenic agents.
Bernardi et al. (2013)
11 more

1 mention without citation

Predicting binding sites from unbound versus bound protein structures.
Clark et al. (2020)