› 1a1p

Solution NMR

COMPSTATIN, NMR, 21 STRUCTURES

Released:
DOI: 10.2210/pdb1a1p/pdb
PDB entry 1a1p coloured by chain, ensemble of 21 models, front view.
PDB entry 1a1p coloured by chain, ensemble of 21 models, side view.
PDB entry 1a1p coloured by chain, ensemble of 21 models, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of Compstatin, a potent complement inhibitor.
Morikis D, Assa-Munt N, Sahu A, Lambris JD
Protein Sci. 7 619-27 (1998)
PMID: 9541394

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162093 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
COMPSTATIN Chain: A
Molecule details ›
Chain: A
Length: 14 amino acids
Theoretical weight: 1.55 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: HYBRID DISTANCE GEOMETRY-RESTRAINED SIMULATED ANNEALING
Expression system: Not provided

Quick links

Citations

17 review citations

Complement System Part I - Molecular Mechanisms of Activation and Regulation.
Merle et al. (2015)
16 more

8 mentions without citation

Compstatin: a complement inhibitor on its way to clinical application.
Ricklin et al. (2008)
7 more