› 1a1x

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF MTCP-1 INVOLVED IN T CELL MALIGNANCIES

Released:
DOI: 10.2210/pdb1a1x/pdb
PDB entry 1a1x coloured by chain, front view.
PDB entry 1a1x coloured by chain, side view.
PDB entry 1a1x coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of MTCP-1: implications for role of TCL-1 and MTCP-1 in T cell malignancies.
Fu ZQ, Du Bois GC, Song SP, Kulikovskaya I, Virgilio L, Rothstein JL, Croce CM, Weber IT, Harrison RW
Proc. Natl. Acad. Sci. U.S.A. 95 3413-8 (1998)
PMID: 9520380

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157456 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein p13 MTCP-1 Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 12.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P56278 (Residues: 2-107; Coverage: 99%)
Gene names: C6.1B, MTCP1
Sequence domains: TCL1/MTCP1 family
Structure domains: TCL1/MTCP1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P6222
Unit cell:
a: 62.665Å b: 62.665Å c: 85.962Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.211 0.211 0.253
Expression system: Escherichia coli

Quick links

Citations

5 review citations

The lipocalin protein family: structural and sequence overview.
Flower et al. (2000)
4 more

12 mentions without citation

Use of a structural alphabet for analysis of short loops connecting repetitive structures.
Fourrier et al. (2004)
11 more