› 1a83

Solution NMR

INTRAMOLECULAR I-MOTIF, NMR, 6 STRUCTURES

Released:
DOI: 10.2210/pdb1a83/pdb
PDB entry 1a83 coloured by chain, ensemble of 6 models, front view.
PDB entry 1a83 coloured by chain, ensemble of 6 models, side view.
PDB entry 1a83 coloured by chain, ensemble of 6 models, top view.
Source organism: Synthetic construct
Primary publication:
An intramolecular i-motif: the solution structure and base-pair opening kinetics of d(5mCCT3CCT3ACCT3CC).
Han X, Leroy JL, Guéron M
J Mol Biol 278 949-65 (1998)
PMID: 9600855

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113399 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-(MCY)CTTTCCTTTACCTTTCC-3') Chain: A
Molecule details ›
Chain: A
Length: 18 nucleotides
Theoretical weight: 5.25 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MCY 1 x MCY

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Refinement method: molecular dynamics
Expression system: Not provided

Quick links

Citations

6 review citations

i-Motif DNA: structure, stability and targeting with ligands.
Day et al. (2014)
5 more

4 mentions without citation

Although divergent in residues of the peptide binding site, conserved chimpanzee Patr-AL and polymorphic human HLA-A*02 have overlapping peptide-binding repertoires.
Gleimer et al. (2011)
3 more