PDB 1a84 structure summary ‹ Protein Data Bank in Europe (PDBe)

Solution NMR

NMR SOLUTION STRUCTURE OF A DNA DODECAMER DUPLEX CONTAINING A CIS-DIAMMINEPLATINUM(II) D(GPG) INTRASTRAND CROSS-LINK, THE MAJOR ADDUCT OF THE ANTICANCER DRUG CISPLATIN, 1 STRUCTURE

Released: 25 Nov 1998

DOI: 10.2210/pdb1a84/pdb

Source organism: Synthetic construct

Primary publication:
NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin.

Gelasco A, Lippard SJ

Biochemistry 37 9230-9 (1998)

PMID: 9649303

Function and Biology Details

Biochemical function:

not assigned

Biological process:

not assigned

Cellular component:

not assigned

Structure analysis Details

Assembly composition:

hetero dimer (preferred)

Assembly name:

DNA (preferred)

PDBe Complex ID:

PDB-CPX-113400 (preferred)

Entry contents:

2 distinct DNA molecules

Macromolecules (2 distinct):

DNA D(CCTCTG*G*TCTCC) Chain: A

Molecule details ›

Chain: A
Length: 12 nucleotides
Theoretical weight: 3.57 KDa
Source organism: Synthetic construct
Expression system: Not provided

DNA D(GGAGACCAGAGG) Chain: B

Molecule details ›

Chain: B
Length: 12 nucleotides
Theoretical weight: 3.76 KDa
Source organism: Synthetic construct
Expression system: Not provided