1acy

X-ray diffraction
3Å resolution

CRYSTAL STRUCTURE OF THE PRINCIPAL NEUTRALIZING SITE OF HIV-1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-208679 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
IGG1-KAPPA 59.1 FAB (LIGHT CHAIN) Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.68 KDa
Source organism: Mus musculus
Expression system: Not provided
Structure domains: Immunoglobulins
Ig gamma-1 chain C region, membrane-bound form Chain: H
Molecule details ›
Chain: H
Length: 221 amino acids
Theoretical weight: 24.21 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P01869 (Residues: 1-100; Coverage: 25%)
Gene names: Igh-4, Ighg1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Surface protein gp120 Chain: P
Molecule details ›
Chain: P
Length: 24 amino acids
Theoretical weight: 2.81 KDa
Source organism: HIV-1 M:B_MN
Expression system: Not provided
UniProt:
  • Canonical: P05877 (Residues: 306-328; Coverage: 3%)
Gene name: env

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2221
Unit cell:
a: 89.7Å b: 154Å c: 121.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 not available
Expression system: Not provided