› 1adl

X-ray diffraction
1.6Å resolution

ADIPOCYTE LIPID BINDING PROTEIN COMPLEXED WITH ARACHIDONIC ACID: X-RAY CRYSTALLOGRAPHIC AND TITRATION CALORIMETRY STUDIES

Released:
DOI: 10.2210/pdb1adl/pdb
PDB entry 1adl coloured by chain, front view.
PDB entry 1adl coloured by chain, side view.
PDB entry 1adl coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Adipocyte lipid-binding protein complexed with arachidonic acid. Titration calorimetry and X-ray crystallographic studies.
LaLonde JM, Levenson MA, Roe JJ, Bernlohr DA, Banaszak LJ
J Biol Chem 269 25339-47 (1994)
PMID: 7929228

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137406 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, adipocyte Chain: A
Molecule details ›
Chain: A
Length: 131 amino acids
Theoretical weight: 14.59 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P04117 (Residues: 2-132; Coverage: 99%)
Gene names: Ap2, Fabp4
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

2 bound ligands:
Ligand ACD 1 x ACD
Ligand PPI 1 x PPI
2 modified residues:
Ligand MHO 1 x MHO
Ligand CSD 1 x CSD

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 120.54Å b: 37.7Å c: 28.57Å
α: 90° β: 92.34° γ: 90°
R-values:
R R work R free
0.188 0.188 0.22
Expression system: Not provided

Quick links

Citations

9 review citations

The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism.
Chmurzyńska A. (2006)
8 more

17 mentions without citation

Impact of Intracellular Lipid Binding Proteins on Endogenous and Xenobiotic Ligand Metabolism and Disposition.
Yabut et al. (2023)
16 more