› 1aei

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURE OF THE ANNEXIN XII HEXAMER

Released:
DOI: 10.2210/pdb1aei/pdb
PDB entry 1aei coloured by chain, front view.
PDB entry 1aei coloured by chain, side view.
PDB entry 1aei coloured by chain, top view.
Source organism: Hydra vulgaris
Primary publication:
Crystal structure of the annexin XII hexamer and implications for bilayer insertion.
Luecke H, Chang BT, Mailliard WS, Schlaepfer DD, Haigler HT
Nature 378 512-5 (1995)
PMID: 7477411

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150682 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Annexin-B12 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 315 amino acids
Theoretical weight: 35.02 KDa
Source organism: Hydra vulgaris
Expression system: Escherichia coli
UniProt:
  • Canonical: P26256 (Residues: 2-316; Coverage: 100%)
Gene name: ANXB12
Sequence domains: Annexin
Structure domains: Annexin

Ligands and Environments

1 bound ligand:
Ligand CA 24 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P21
Unit cell:
a: 71.2Å b: 179.2Å c: 100.7Å
α: 90° β: 97.6° γ: 90°
R-values:
R R work R free
0.236 0.236 0.278
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Annexins: from structure to function.
Gerke et al. (2002)
14 more

8 mentions without citation

Annexin-phospholipid interactions. Functional implications.
Lizarbe et al. (2013)
7 more