› 1ag3

Solution NMR

DUPLEX OLIGODEOXYNUCLEOTIDE CONTAINING PROPANODEOXYGUANOSINE OPPOSITE A TWO-BASE DELETION, NMR, MINIMIZED AVERAGE STRUCTURE

Released:
DOI: 10.2210/pdb1ag3/pdb
PDB entry 1ag3 coloured by chain, front view.
PDB entry 1ag3 coloured by chain, side view.
PDB entry 1ag3 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structure of a duplex oligodeoxynucleotide containing propanodeoxyguanosine opposite a two-base deletion in the (CpG)3 frame shift hotspot of Salmonella typhimurium hisD3052 determined by 1H NMR and restrained molecular dynamics.
Weisenseel JP, Moe JG, Reddy GR, Marnett LJ, Stone MP
Biochemistry 34 50-64 (1995)
PMID: 7819223

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113414 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*AP*TP*CP*GP*CP*PP*CP*GP*GP*CP*AP*TP*G)-3') Chain: A
Molecule details ›
Chain: A
Length: 13 nucleotides
Theoretical weight: 4.03 KDa
Source organism: Synthetic construct
Expression system: Not provided
DNA (5'-D(*CP*AP*TP*GP*CP*CP*GP*CP*GP*AP*T)-3') Chain: B
Molecule details ›
Chain: B
Length: 11 nucleotides
Theoretical weight: 3.33 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand P 1 x P

Experiments and Validation Details

Entry percentile scores
Refinement method: NOE-RESTRAINED MOLECULAR DYNAMICS/SIMULATED ANNEALING
Expression system: Not provided

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Citations

1 review citation

Chemistry and structural biology of DNA damage and biological consequences.
Stone et al. (2011)
9 other articles