› 1agl

X-ray diffraction
2.2Å resolution

STRUCTURE OF A DNA-BISDAUNOMYCIN COMPLEX

Released:
DOI: 10.2210/pdb1agl/pdb
PDB entry 1agl coloured by chain, front view.
PDB entry 1agl coloured by chain, side view.
PDB entry 1agl coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Structure of a DNA-bisdaunomycin complex.
Hu GG, Shui X, Leng F, Priebe W, Chaires JB, Williams LD
Biochemistry 36 5940-6 (1997)
PMID: 9166763

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113418 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*GP*AP*TP*CP*G)-3') Chain: A
Molecule details ›
Chain: A
Length: 6 nucleotides
Theoretical weight: 1.81 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand BDA 1 x BDA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P41212
Unit cell:
a: 28.27Å b: 28.27Å c: 53.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.199 0.314
Expression system: Not provided

Quick links

Citations

7 review citations

Calorimetry and thermodynamics in drug design.
Chaires JB. (2008)
6 more

1 mention without citation

Unraveling the sequence-dependent polymorphic behavior of d(CpG) steps in B-DNA.
Dans et al. (2014)