Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Translational (tr)-type GTP-binding domain
- Translation elongation factor EFTs/EF1B
- Elongation factor Ts, dimerisation domain superfamily
- Translation elongation factor Ts, conserved site
- P-loop containing nucleoside triphosphate hydrolase
- Translation elongation factor EFTs/EF1B, dimerisation
- UBA-like superfamily
- Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
8 more domains
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Elongation factor Ts and Elongation factor Tu-A (preferred)
PDBe Complex ID:
PDB-CPX-155149 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Elongation factor Tu-A
Molecule details ›
Chains: A, B, E, F
Length: 405 amino acids
Theoretical weight: 44.74 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 405 amino acids
Theoretical weight: 44.74 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
- Canonical:
P60338 (Residues: 2-406; Coverage: 100%)
Sequence domains:
- Elongation factor Tu GTP binding domain
- Elongation factor Tu domain 2
- Elongation factor Tu C-terminal domain
Elongation factor Ts
Molecule details ›
Chains: C, D, G, H
Length: 196 amino acids
Theoretical weight: 22.45 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
Sequence domains: Elongation factor TS
Structure domains:
Length: 196 amino acids
Theoretical weight: 22.45 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli
UniProt:
- Canonical: P43895 (Residues: 1-196; Coverage: 100%)
Sequence domains: Elongation factor TS
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X25
Spacegroup:
P21
Expression system: Escherichia coli
