› 1akg

X-ray diffraction
1.1Å resolution

ALPHA-CONOTOXIN PNIB FROM CONUS PENNACEUS

Released:
DOI: 10.2210/pdb1akg/pdb
PDB entry 1akg coloured by chain, front view.
PDB entry 1akg coloured by chain, side view.
PDB entry 1akg coloured by chain, top view.
Source organism: Conus pennaceus
Primary publication:
Crystal structure at 1.1 A resolution of alpha-conotoxin PnIB: comparison with alpha-conotoxins PnIA and GI.
Hu SH, Gehrmann J, Alewood PF, Craik DJ, Martin JL
Biochemistry 36 11323-30 (1997)
PMID: 9298951

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156282 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-conotoxin PnIB Chain: A
Molecule details ›
Chain: A
Length: 17 amino acids
Theoretical weight: 1.64 KDa
Source organism: Conus pennaceus
Expression system: Not provided
UniProt:
  • Canonical: P50985 (Residues: 45-60; Coverage: 40%)
Sequence domains: Alpha conotoxin precursor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P212121
Unit cell:
a: 14.6Å b: 26.1Å c: 29.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.147 0.147 0.157
Expression system: Not provided

Quick links

Citations

11 review citations

Conus peptides targeted to specific nicotinic acetylcholine receptor subtypes.
McIntosh et al. (1999)
10 more

12 mentions without citation

Discovery, synthesis, and structure-activity relationships of conotoxins.
Akondi et al. (2014)
11 more