› 1anv

X-ray diffraction
2.7Å resolution

ADENOVIRUS 5 DBP/URANYL FLUORIDE SOAK

Released:
DOI: 10.2210/pdb1anv/pdb
PDB entry 1anv coloured by chain, front view.
PDB entry 1anv coloured by chain, side view.
PDB entry 1anv coloured by chain, top view.
Source organism: Human adenovirus 5
Primary publication:
Conformational change of the adenovirus DNA-binding protein induced by soaking crystals with K3UO2F5 solutions.
Kanellopoulos PN, Tsernoglou D, van der Vliet PC, Tucker PA
Acta Crystallogr D Biol Crystallogr 52 942-5 (1996)
PMID: 15299602

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136673 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA-binding protein Chain: A
Molecule details ›
Chain: A
Length: 356 amino acids
Theoretical weight: 39.9 KDa
Source organism: Human adenovirus 5
UniProt:
  • Canonical: P03265 (Residues: 174-529; Coverage: 67%)
Gene name: DBP
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand ZN 2 x ZN
Ligand IUM 4 x IUM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MACSCIENCE M18X
Spacegroup: P212121
Unit cell:
a: 79.7Å b: 75.6Å c: 60.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.204 0.31

Quick links

Citations

1 mention without citation

The critical protein interactions and structures that elicit growth deregulation in cancer and viral replication.
Ou et al. (2011)