› 1ar2

X-ray diffraction
2.8Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134438 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Immunoglobulin kappa variable 1D-33 Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 11.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01593 (Residues: 23-117; Coverage: 100%)
Gene name: IGKV1D-33
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7A
Spacegroup: P6122
Unit cell:
a: 52.8Å b: 52.8Å c: 158.2Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.28 not available 0.415
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Stability engineering of antibody single-chain Fv fragments.
Wörn et al. (2001)
4 more

1 mention without citation

Effect of single point mutations in a form of systemic amyloidosis.
Bhavaraju et al. (2015)