1asv

X-ray diffraction
2.2Å resolution

Avian sarcoma virus integrase catalytic core domain

Released:

Function and Biology Details

Reactions catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Endonucleolytic cleavage to 5'-phosphomonoester.
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131654 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrase Chain: A
Molecule details ›
Chain: A
Length: 162 amino acids
Theoretical weight: 17.94 KDa
Source organism: Avian sarcoma virus
Expression system: Escherichia coli
UniProt:
  • Canonical: O92956 (Residues: 1331-1487; Coverage: 10%)
Gene name: gag-pol
Sequence domains: Integrase core domain
Structure domains: Ribonuclease H-like superfamily/Ribonuclease H

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
Spacegroup: P43212
Unit cell:
a: 66.55Å b: 66.55Å c: 80.87Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.142 not available 0.234
Expression system: Escherichia coli