› 1aua

X-ray diffraction
2.5Å resolution

PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P FROM SACCHAROMYCES CEREVISIAE

Released:
DOI: 10.2210/pdb1aua/pdb
PDB entry 1aua coloured by chain, front view.
PDB entry 1aua coloured by chain, side view.
PDB entry 1aua coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol-transfer protein.
Sha B, Phillips SE, Bankaitis VA, Luo M
Nature 391 506-10 (1998)
PMID: 9461221

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150196 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SEC14 cytosolic factor Chain: A
Molecule details ›
Chain: A
Length: 296 amino acids
Theoretical weight: 34.05 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P24280 (Residues: 4-299; Coverage: 97%)
Gene names: PIT1, SEC14, YM9582.04, YMR079W
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand BOG 2 x BOG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P3221
Unit cell:
a: 88.971Å b: 88.971Å c: 111.339Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.211 0.211 0.273
Expression system: Escherichia coli

Quick links

Citations

51 review citations

Phosphoinositides: tiny lipids with giant impact on cell regulation.
Balla T. (2013)
50 more

34 mentions without citation

The Sec14 superfamily and mechanisms for crosstalk between lipid metabolism and lipid signaling.
Bankaitis et al. (2010)
33 more