› 1avd

X-ray diffraction
2.7Å resolution

THREE-DIMENSIONAL STRUCTURE OF THE TETRAGONAL CRYSTAL FORM OF EGG-WHITE AVIDIN IN ITS FUNCTIONAL COMPLEX WITH BIOTIN AT 2.7 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1avd/pdb
PDB entry 1avd coloured by chain, front view.
PDB entry 1avd coloured by chain, side view.
PDB entry 1avd coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Three-dimensional structure of the tetragonal crystal form of egg-white avidin in its functional complex with biotin at 2.7 A resolution.
Pugliese L, Coda A, Malcovati M, Bolognesi M
J Mol Biol 231 698-710 (1993)
PMID: 8515446

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136083 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Avidin Chains: A, B
Molecule details ›
Chains: A, B
Length: 128 amino acids
Theoretical weight: 14.35 KDa
Source organism: Gallus gallus
Expression system: Not provided
UniProt:
  • Canonical: P02701 (Residues: 25-152; Coverage: 100%)
Gene name: AVD
Sequence domains: Avidin family
Structure domains: Avidin-like

Ligands and Environments

2 bound ligands:
Ligand NAG 1 x NAG
Ligand BTN 2 x BTN
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P42212
Unit cell:
a: 80.15Å b: 80.15Å c: 85.28Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 not available not available
Expression system: Not provided

Quick links

Citations

7 review citations

On the biomedical promise of cell penetrating peptides: limits versus prospects.
Foerg et al. (2008)
6 more

29 mentions without citation

Assessing the performance of the MM/PBSA and MM/GBSA methods. 1. The accuracy of binding free energy calculations based on molecular dynamics simulations.
Hou et al. (2011)
28 more