Function and Biology Details
Reaction catalysed:
More restricted specificity than pepsin A, but shows preferential cleavage at Tyr-|- bonds. High activity on hemoglobin.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Gastricsin (preferred)
PDBe Complex ID:
PDB-CPX-148859 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Gastricsin
Molecule details ›
Chains: P, Q
Length: 26 amino acids
Theoretical weight: 2.98 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: A1 Propeptide
Length: 26 amino acids
Theoretical weight: 2.98 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P20142 (Residues: 17-42; Coverage: 7%)
Sequence domains: A1 Propeptide
Gastricsin
Molecule details ›
Chains: A, J
Length: 329 amino acids
Theoretical weight: 35.46 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains: Eukaryotic aspartyl protease
Structure domains: Acid Proteases
Length: 329 amino acids
Theoretical weight: 35.46 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P20142 (Residues: 60-388; Coverage: 88%)
Sequence domains: Eukaryotic aspartyl protease
Structure domains: Acid Proteases
