› 1axh

Solution NMR

ATRACOTOXIN-HVI FROM HADRONYCHE VERSUTA (AUSTRALIAN FUNNEL-WEB SPIDER, NMR, 20 STRUCTURES

Released:
DOI: 10.2210/pdb1axh/pdb
PDB entry 1axh coloured by chain, ensemble of 20 models, front view.
PDB entry 1axh coloured by chain, ensemble of 20 models, side view.
PDB entry 1axh coloured by chain, ensemble of 20 models, top view.
Source organism: Hadronyche versuta
Primary publication:
The structure of a novel insecticidal neurotoxin, omega-atracotoxin-HV1, from the venom of an Australian funnel web spider.
Fletcher JI, Smith R, O'Donoghue SI, Nilges M, Connor M, Howden ME, Christie MJ, King GF
Nat Struct Biol 4 559-66 (1997)
PMID: 9228949

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157423 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Omega-hexatoxin-Hv1a Chain: A
Molecule details ›
Chain: A
Length: 37 amino acids
Theoretical weight: 4.06 KDa
Source organism: Hadronyche versuta
Expression system: Not provided
UniProt:
  • Canonical: P56207 (Residues: 1-37; Coverage: 100%)
Sequence domains: Omega-atracotoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND DYNAMICAL SIMULATED ANNEALING
Expression system: Not provided

Quick links

Citations

26 review citations

The cystine knot motif in toxins and implications for drug design.
Craik et al. (2001)
25 more

7 mentions without citation

Spider-venom peptides as bioinsecticides.
Windley et al. (2012)
6 more