› 1axu

Solution NMR

SOLUTION NMR STRUCTURE OF THE [AP]DG ADDUCT OPPOSITE DA IN A DNA DUPLEX, NMR, 9 STRUCTURES

Released:
DOI: 10.2210/pdb1axu/pdb
PDB entry 1axu coloured by chain, ensemble of 9 models, front view.
PDB entry 1axu coloured by chain, ensemble of 9 models, side view.
PDB entry 1axu coloured by chain, ensemble of 9 models, top view.
Source organism: Synthetic construct
Primary publication:
Solution structure of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dA in a DNA duplex.
Gu Z, Gorin A, Krishnasamy R, Hingerty BE, Basu AK, Broyde S, Patel DJ
Biochemistry 38 10843-54 (1999)
PMID: 10451381

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113449 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA DUPLEX D(CCATC-[AP]G-CTACC)D(GGTAGAGATGG) Chain: A
Molecule details ›
Chain: A
Length: 11 nucleotides
Theoretical weight: 3.25 KDa
Source organism: Synthetic construct
Expression system: Not provided
DNA DUPLEX D(CCATC-[AP]G-CTACC)D(GGTAGAGATGG) Chain: B
Molecule details ›
Chain: B
Length: 11 nucleotides
Theoretical weight: 3.48 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand AP 1 x AP
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: RELAXATION MATRIX REFINEMENT
Expression system: Not provided

Quick links

Citations

4 review citations

Biomonitoring of arylamines and nitroarenes.
Sabbioni et al. (2002)
3 more