› 1ayo

X-ray diffraction
1.9Å resolution

RECEPTOR BINDING DOMAIN OF BOVINE ALPHA-2-MACROGLOBULIN

Released:
DOI: 10.2210/pdb1ayo/pdb
PDB entry 1ayo coloured by chain, front view.
PDB entry 1ayo coloured by chain, side view.
PDB entry 1ayo coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Crystal structure of the receptor-binding domain of alpha 2-macroglobulin.
Jenner L, Husted L, Thirup S, Sottrup-Jensen L, Nyborg J
Structure 6 595-604 (1998)
PMID: 9634697

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181984 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Alpha-2-macroglobulin Chains: A, B
Molecule details ›
Chains: A, B
Length: 130 amino acids
Theoretical weight: 14.51 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: Q7SIH1 (Residues: 1375-1504; Coverage: 9%)
Gene name: A2M
Sequence domains: A-macroglobulin receptor binding domain
Structure domains: Alpha-macroglobulin, receptor-binding domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3121
Unit cell:
a: 107.57Å b: 107.57Å c: 72.229Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.197 not available 0.239

Quick links

Citations

3 review citations

Integrin structure: new twists and turns in dynamic cell adhesion.
Arnaout MA. (2002)
2 more

8 mentions without citation

A novel variant of the immunoglobulin fold in surface adhesins of Staphylococcus aureus: crystal structure of the fibrinogen-binding MSCRAMM, clumping factor A.
Deivanayagam et al. (2002)
7 more