› 1b08

X-ray diffraction
2.3Å resolution

LUNG SURFACTANT PROTEIN D (SP-D) (FRAGMENT)

Released:
DOI: 10.2210/pdb1b08/pdb
PDB entry 1b08 coloured by chain, front view.
PDB entry 1b08 coloured by chain, side view.
PDB entry 1b08 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the trimeric alpha-helical coiled-coil and the three lectin domains of human lung surfactant protein D.
Håkansson K, Lim NK, Hoppe HJ, Reid KB
Structure 7 255-64 (1999)
PMID: 10368295

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152870 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pulmonary surfactant-associated protein D Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 158 amino acids
Theoretical weight: 17.06 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P35247 (Residues: 218-375; Coverage: 45%)
Gene names: COLEC7, PSPD, SFTP4, SFTPD
Sequence domains:
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

1 bound ligand:
Ligand CA 9 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 55.96Å b: 109.72Å c: 56.09Å
α: 90° β: 92.2° γ: 90°
R-values:
R R work R free
0.209 0.209 0.271
Expression system: Komagataella pastoris

Quick links

Citations

21 review citations

The C-type lectin-like domain superfamily.
Zelensky et al. (2005)
20 more

4 mentions without citation

Role of the retinal vascular endothelial cell in ocular disease.
Bharadwaj et al. (2013)
3 more