› 1b0s

Solution NMR

BINDING OF AR-1-144, A TRI-IMIDAZOLE DNA MINOR GROOVE BINDER, TO CCGG SEQUENCE ANALYZED BY NMR SPECTROSCOPY

Released:
DOI: 10.2210/pdb1b0s/pdb
PDB entry 1b0s coloured by chain, front view.
PDB entry 1b0s coloured by chain, side view.
PDB entry 1b0s coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Binding of AR-1-144, a tri-imidazole DNA minor groove binder, to CCGG sequence analyzed by NMR spectroscopy.
Yang XL, Kaenzig C, Lee M, Wang AH
Eur J Biochem 263 646-55 (1999)
PMID: 10469127

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113455 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*GP*AP*AP*CP*CP*GP*GP*TP*TP*C)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 10 nucleotides
Theoretical weight: 3.05 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand AR1 2 x AR1
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: NOE-RMD
Expression system: Not provided

Quick links

Citations

12 citation in other articles

Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove.
Kielkopf et al. (2000)
11 more

1 mention without citation

Conformational modulation of DNA by polyamide binding: structural effects of f-Im-Py-Im based derivatives on 5'-ACGCGT-3'.
Wang et al. (2013)