› 1b8k

X-ray diffraction
2.15Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149052 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neurotrophin-3 Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20783 (Residues: 139-257; Coverage: 50%)
Gene name: NTF3
Sequence domains: Nerve growth factor family
Structure domains: Cystine-knot cytokines

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P21212
Unit cell:
a: 38.3Å b: 52.3Å c: 67.7Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.238 0.238 0.302
Expression system: Escherichia coli

Quick links

Citations

13 review citations

Neurotrophins: roles in neuronal development and function.
Huang et al. (2001)
12 more

2 mentions without citation

Quercetin conjugated with superparamagnetic iron oxide nanoparticles improves learning and memory better than free quercetin via interacting with proteins involved in LTP.
Amanzadeh et al. (2019)
1 more