› 1b9k

X-ray diffraction
1.9Å resolution

ALPHA-ADAPTIN APPENDAGE DOMAIN, FROM CLATHRIN ADAPTOR AP2

Released:
DOI: 10.2210/pdb1b9k/pdb
PDB entry 1b9k coloured by chain, front view.
PDB entry 1b9k coloured by chain, side view.
PDB entry 1b9k coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain.
Owen DJ, Vallis Y, Noble ME, Hunter JB, Dafforn TR, Evans PR, McMahon HT
Cell 97 805-15 (1999)
PMID: 10380931

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148055 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AP-2 complex subunit alpha-2 Chain: A
Molecule details ›
Chain: A
Length: 238 amino acids
Theoretical weight: 27.02 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P17427 (Residues: 701-938; Coverage: 25%)
Gene names: Adtab, Ap2a2
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P1
Unit cell:
a: 39.86Å b: 40.87Å c: 42.47Å
α: 99.4° β: 95.29° γ: 113.69°
R-values:
R R work R free
0.172 0.163 0.221
Expression system: Escherichia coli

Quick links

Citations

39 review citations

Biological basket weaving: formation and function of clathrin-coated vesicles.
Brodsky et al. (2001)
38 more

11 mentions without citation

Molecular structure, function, and dynamics of clathrin-mediated membrane traffic.
Kirchhausen et al. (2014)
10 more