› 1bar

X-ray diffraction
2.7Å resolution

THREE-DIMENSIONAL STRUCTURES OF ACIDIC AND BASIC FIBROBLAST GROWTH FACTORS

Released:
DOI: 10.2210/pdb1bar/pdb
PDB entry 1bar coloured by chain, front view.
PDB entry 1bar coloured by chain, side view.
PDB entry 1bar coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Three-dimensional structures of acidic and basic fibroblast growth factors.
Zhu X, Komiya H, Chirino A, Faham S, Fox GM, Arakawa T, Hsu BT, Rees DC
Science 251 90-3 (1991)
PMID: 1702556

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-137304 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 140 amino acids
Theoretical weight: 15.79 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P03968 (Residues: 16-155; Coverage: 90%)
Gene names: AFGF, FGF1, FGFA, HBGF-1
Sequence domains: Fibroblast growth factor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3121
Unit cell:
a: 78.6Å b: 78.6Å c: 115.9Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.177 0.177 not available
Expression system: Escherichia coli

Quick links

Citations

42 review citations

Fibroblast growth factors.
Ornitz et al. (2001)
41 more

8 mentions without citation

Zeolites in Adsorption Processes: State of the Art and Future Prospects.
Pérez-Botella et al. (2022)
7 more