› 1bc9

Solution NMR

CYTOHESIN-1/B2-1 SEC7 DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE

Released:
DOI: 10.2210/pdb1bc9/pdb
PDB entry 1bc9 coloured by chain, front view.
PDB entry 1bc9 coloured by chain, side view.
PDB entry 1bc9 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the cytohesin-1 (B2-1) Sec7 domain and its interaction with the GTPase ADP ribosylation factor 1.
Betz SF, Schnuchel A, Wang H, Olejniczak ET, Meadows RP, Lipsky BP, Harris EA, Staunton DE, Fesik SW
Proc Natl Acad Sci U S A 95 7909-14 (1998)
PMID: 9653114

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172291 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytohesin-1 Chain: A
Molecule details ›
Chain: A
Length: 200 amino acids
Theoretical weight: 23.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15438 (Residues: 58-256; Coverage: 50%)
Gene names: CYTH1, D17S811E, PSCD1
Sequence domains: Sec7 domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY/ SIMULATED ANNEALING
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

5 review citations

Turning on ARF: the Sec7 family of guanine-nucleotide-exchange factors.
Jackson et al. (2000)
4 more

1 mention without citation

Solution structure of the cytohesin-1 (B2-1) Sec7 domain and its interaction with the GTPase ADP ribosylation factor 1.
Betz et al. (1998)