› 1bd7

X-ray diffraction
2.78Å resolution

CIRCULARLY PERMUTED BB2-CRYSTALLIN

Released:
DOI: 10.2210/pdb1bd7/pdb
PDB entry 1bd7 coloured by chain, front view.
PDB entry 1bd7 coloured by chain, side view.
PDB entry 1bd7 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Circular permutation of betaB2-crystallin changes the hierarchy of domain assembly.
Wright G, Basak AK, Wieligmann K, Mayr EM, Slingsby C
Protein Sci 7 1280-5 (1998)
PMID: 9655330

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158664 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-crystallin B2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 176 amino acids
Theoretical weight: 20.15 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P62697 (Residues: 106-193; Coverage: 43%)
Gene name: Crybb2
Sequence domains: Beta/Gamma crystallin
Structure domains: Crystallins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P1
Unit cell:
a: 39Å b: 48.5Å c: 54.5Å
α: 66.7° β: 74.9° γ: 77.5°
R-values:
R R work R free
0.19 0.19 0.278
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Ageing and vision: structure, stability and function of lens crystallins.
Bloemendal et al. (2004)
6 more

2 mentions without citation

CPSARST: an efficient circular permutation search tool applied to the detection of novel protein structural relationships.
Lo et al. (2008)
1 more