› 1be4

X-ray diffraction
2.4Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156474 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoside diphosphate kinase A 2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 151 amino acids
Theoretical weight: 17.19 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P52175 (Residues: 2-152; Coverage: 99%)
Gene name: NME1-2
Sequence domains: Nucleoside diphosphate kinase
Structure domains: Nucleoside diphosphate kinase-like domain

Ligands and Environments

1 bound ligand:
Ligand PCG 3 x PCG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SIEMENS
Spacegroup: P43212
Unit cell:
a: 128.61Å b: 128.61Å c: 88.18Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 not available not available
Expression system: Escherichia coli

Quick links

Citations

3 review citations

The catalytic mechanism of nucleoside diphosphate kinases.
Lascu et al. (2000)
2 more

3 mentions without citation

SwoHp, a nucleoside diphosphate kinase, is essential in Aspergillus nidulans.
Lin et al. (2003)
2 more