› 1bf0

Solution NMR

CALCICLUDINE (CAC) FROM GREEN MAMBA DENDROASPIS ANGUSTICEPS, NMR, 15 STRUCTURES

Released:
DOI: 10.2210/pdb1bf0/pdb
PDB entry 1bf0 coloured by chain, ensemble of 15 models, front view.
PDB entry 1bf0 coloured by chain, ensemble of 15 models, side view.
PDB entry 1bf0 coloured by chain, ensemble of 15 models, top view.
Source organism: Dendroaspis angusticeps
Primary publication:
Conformational and functional variability supported by the BPTI fold: solution structure of the Ca2+ channel blocker calcicludine.
Gilquin B, Lecoq A, Desné F, Guenneugues M, Zinn-Justin S, Ménez A
Proteins 34 520-32 (1999)
PMID: 10081964

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160545 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kunitz-type serine protease inhibitor homolog calcicludine Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 7 KDa
Source organism: Dendroaspis angusticeps
UniProt:
  • Canonical: P81658 (Residues: 1-60; Coverage: 100%)
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: MD- BASED SIMULATED ANNEALING WITH AMBIGOUS DISTANCE CONSTRAINTS

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Citations

5 review citations

Anticoagulant proteins from snake venoms: structure, function and mechanism.
Kini RM. (2006)
4 more

5 mentions without citation

ANTIAGE-DB: A Database and Server for the Prediction of Anti-Aging Compounds Targeting Elastase, Hyaluronidase, and Tyrosinase.
Papaemmanouil et al. (2022)
4 more