› 1bg5

X-ray diffraction
2.6Å resolution

CRYSTAL STRUCTURE OF THE ANKYRIN BINDING DOMAIN OF ALPHA-NA,K-ATPASE AS A FUSION PROTEIN WITH GLUTATHIONE S-TRANSFERASE

Released:
DOI: 10.2210/pdb1bg5/pdb
PDB entry 1bg5 coloured by chain, front view.
PDB entry 1bg5 coloured by chain, side view.
PDB entry 1bg5 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Structure of the ankyrin-binding domain of alpha-Na,K-ATPase.
Zhang Z, Devarajan P, Dorfman AL, Morrow JS
J Biol Chem 273 18681-4 (1998)
PMID: 9668035

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140160 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase class-mu 26 kDa isozyme Chain: A
Molecule details ›
Chain: A
Length: 254 amino acids
Theoretical weight: 29.53 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P08515 (Residues: 1-218; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P43212
Unit cell:
a: 92.17Å b: 92.17Å c: 57.57Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.359
Expression system: Escherichia coli

Quick links

Citations

21 review citations

Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues.
Bennett et al. (2001)
20 more

3 mentions without citation

STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3.
Liu et al. (2005)
2 more