› 1bge

X-ray diffraction
2.2Å resolution

CRYSTAL STRUCTURE OF CANINE AND BOVINE GRANULOCYTE-COLONY STIMULATING FACTOR (G-CSF)

Released:
DOI: 10.2210/pdb1bge/pdb
PDB entry 1bge coloured by chain, front view.
PDB entry 1bge coloured by chain, side view.
PDB entry 1bge coloured by chain, top view.
Source organism: Canis lupus familiaris
Primary publication:
Crystal structure of canine and bovine granulocyte-colony stimulating factor (G-CSF).
Lovejoy B, Cascio D, Eisenberg D
J Mol Biol 234 640-53 (1993)
PMID: 7504736

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153041 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Granulocyte colony-stimulating factor Chains: A, B
Molecule details ›
Chains: A, B
Length: 175 amino acids
Theoretical weight: 18.87 KDa
Source organism: Canis lupus familiaris
Expression system: Not provided
UniProt:
  • Canonical: P35834 (Residues: 1-175; Coverage: 100%)
Gene name: CSF3
Sequence domains: Granulocyte colony-stimulating factor
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 53.2Å b: 35.9Å c: 91Å
α: 90° β: 101.8° γ: 90°
R-values:
R R work R free
0.193 0.193 not available
Expression system: Not provided

Quick links

Citations

4 review citations

Interleukin-6: structure-function relationships.
Simpson et al. (1997)
3 more

4 mentions without citation

Structural alignment of proteins by a novel TOPOFIT method, as a superimposition of common volumes at a topomax point.
Ilyin et al. (2004)
3 more